Martine Auclair Selected Research

HIV Integrase Inhibitors

1/2022

Inhibition of Adipose Tissue Beiging by HIV Integrase Inhibitors, Dolutegravir and Bictegravir, Is Associated with Adipocyte Hypertrophy, Hypoxia, Elevated Fibrosis, and Insulin Resistance in Simian Adipose Tissue and Human Adipocytes.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Martine Auclair Research Topics

Disease

16	Insulin Resistance 01/2024 - 03/2002
11	Lipodystrophy 02/2020 - 03/2002
7	Inflammation (Inflammations) 01/2020 - 12/2010
3	Hypertriglyceridemia 01/2021 - 12/2007
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 02/2020
3	Familial Partial Lipodystrophy (Dunnigan Syndrome) 12/2019 - 12/2007
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2017 - 12/2010
3	Laminopathies 07/2013 - 12/2007
2	Multiple Myeloma 01/2022 - 10/2019
2	Hypertrophy 01/2022 - 12/2007
2	Lipoatrophic Diabetes Mellitus 01/2022 - 01/2021
2	Obesity 01/2021 - 01/2016
2	Hyperglycemia 02/2020 - 01/2019
2	Hypertension (High Blood Pressure) 04/2013 - 01/2010
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2010 - 12/2007
2	Necrosis 12/2004 - 03/2002
1	Dwarfism 01/2024
1	Hypotrichosis 01/2024
1	Hypoxia (Hypoxemia) 01/2022
1	Fibrosis (Cirrhosis) 01/2022
1	Pulmonary Hypertension 11/2021
1	Esophageal Achalasia (Megaesophagus) 11/2021
1	Congenital Generalized Lipodystrophy (Berardinelli-Seip Congenital Lipodystrophy) 11/2021
1	Non-alcoholic Fatty Liver Disease 01/2021
1	Hypoadiponectinemia 01/2021
1	Body Weight (Weight, Body) 01/2021
1	Lentigo (Lentiginosis) 01/2020
1	Noonan Syndrome (Female Pseudo-Turner Syndrome) 01/2020
1	Weight Gain 01/2020
1	Bone Diseases (Bone Disease) 10/2019
1	Diabetes Mellitus 01/2019
1	Histiocytosis 01/2019
1	Atherosclerosis 02/2016
1	Werner Syndrome (Werner's Syndrome) 07/2013
1	Primary Ovarian Insufficiency 07/2013
1	Hyperandrogenism 07/2013
1	Cardiomyopathies (Cardiomyopathy) 05/2011
1	Fatty Liver 05/2011
1	Progeria (Hutchinson Gilford Syndrome) 05/2011

Drug/Important Bio-Agent (IBA)

5	Insulin (Novolin)FDA Link 01/2022 - 02/2011
4	CytokinesIBA 01/2022 - 11/2003
4	LeptinIBA 01/2021 - 03/2002
4	Ritonavir (Norvir)FDA Link 01/2020 - 12/2010
4	Protease Inhibitors (Protease Inhibitor)IBA 01/2020 - 03/2002
4	Glucose (Dextrose)FDA LinkGeneric 01/2016 - 12/2007
3	Proteins (Proteins, Gene)FDA Link 01/2024 - 10/2019
3	dolutegravirIBA 01/2022 - 01/2017
3	Metformin (Glucophage)FDA LinkGeneric 01/2021 - 07/2013
3	Atazanavir Sulfate (Reyataz)FDA Link 01/2020 - 01/2012
3	HIV Protease InhibitorsIBA 02/2016 - 11/2003
3	prelamin AIBA 02/2016 - 12/2010
3	Messenger RNA (mRNA)IBA 04/2013 - 03/2002
3	LipidsIBA 01/2012 - 03/2002
2	Triglycerides (Triacylglycerol)IBA 11/2021 - 12/2019
2	Maraviroc FDA Link 01/2020 - 01/2017
2	IntegrasesIBA 01/2020 - 01/2017
2	Perilipin-1IBA 12/2019 - 02/2011
2	Pravastatin (Pravachol)FDA LinkGeneric 02/2016 - 01/2014
2	Darunavir (Prezista)FDA Link 01/2014 - 01/2012
2	Lopinavir FDA Link 01/2014 - 01/2012
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2014 - 01/2012
2	LaminsIBA 07/2013 - 05/2011
2	AdiponectinIBA 05/2011 - 12/2004
2	Interleukin-6 (Interleukin 6)IBA 12/2004 - 11/2003
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2004 - 03/2002
1	Insulin-Like Growth Factor I (IGF-1)IBA 01/2024
1	bictegravirIBA 01/2022
1	Thymidine PhosphorylaseIBA 01/2022
1	HIV Integrase InhibitorsIBA 01/2022
1	Hypoxia-Inducible Factor 1IBA 01/2022
1	HDL CholesterolIBA 11/2021
1	Caveolin 1IBA 11/2021
1	LigandsIBA 01/2021
1	SR 3335IBA 01/2021
1	SR 1078IBA 01/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	Epoxy Compounds (Epoxides)IBA 01/2021
1	metreleptinIBA 02/2020
1	Hypoglycemic Agents (Hypoglycemics)IBA 02/2020
1	ChromatinIBA 02/2020
1	Mitogen-Activated Protein KinasesIBA 01/2020
1	Insulin ReceptorIBA 01/2019
1	AntibodiesIBA 01/2019
1	RetinoidsIBA 11/2017
1	Raltegravir Potassium FDA Link 01/2017
1	Integrase InhibitorsIBA 01/2017
1	FTI 277IBA 02/2016
1	Cysteine (L-Cysteine)FDA Link 02/2016
1	AntioxidantsIBA 02/2016
1	AdipokinesIBA 01/2016
1	Small Interfering RNA (siRNA)IBA 01/2016
1	Follicle Stimulating Hormone (Follitropin)FDA Link 07/2013
1	DNA HelicasesIBA 07/2013
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 04/2013
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 04/2013
1	Phosphotransferases (Kinase)IBA 01/2012
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2012

Therapy/Procedure

5	Therapeutics 02/2020 - 03/2002
1	Diet Therapy (Therapy, Diet) 02/2020
1	Drug Therapy (Chemotherapy) 01/2019